Alleleid 7.01

Description:
AlleleID 7.01 | 46,8 MB

AlleleID is a comprehensive desktop tool designed to address the challenges of bacterial identification, pathogen detection or species identification. With ClustalW multiple sequence alignment at its core, AlleleID can be used to design species identification/cross species probes for microarrays or real time PCR including SYBR® Green, TaqMan® MGB, TaqMan® probes, Molecular Beacons and real time PCR primers. AlleleID also offers support for designing microarray experiments for detecting alternative splicing events.

Multiplex ligation-dependent probe amplification (MLPA) assays for copy number and mutation detection
AlleleID is the only program that designs synthetic probes for MLPA or Multiplex Ligation-dependent Probe Amplification technique introduced by MRC Holland enabling the researcher to extend the technique when appropriate kits are unavailable. It is a rapidly growing high throughput method for genetic profiling. It can detect exon deletions, copy number changes, and CpG methylation patterns. It is cost-effective, sensitive, specific and reproducible.

AlleleID also designs mRNA specific, DNA specific and mutation specific MLPA probes for PamGene Arrays. This will enable PamChip® users designing their own probes to detect genes of interest using PamGene’s high precision detection platform. Combining these two technologies, copy number changes and mutation can be easily detected in just 6 hours.

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